WebJan 20, 2024 · Tuberous sclerosis complex (TSC), also known as tuberous sclerosis, is a rare genetic disease that causes non-cancerous (benign) tumors to grow in the brain and several areas of the body, including the spinal cord, nerves, eyes, lung, heart, kidneys, and skin. The name tuberous sclerosis comes from the characteristic tuber or potato-like ... Webdiagnosed with TSC These recommendations are for the care of patients who have already been . diagnosed with definite or possible TSC. They include recommendations for …
Everolimus as adjunctive therapy for tuberous sclerosis complex ...
WebSep 8, 2024 · GENETICS. Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with an incidence of approximately 1 in 5000 to 10,000 live births [ 3-7 ]. It is caused by pathogenic variants in either the TSC1 or the TSC2 genes, which results in overactivation of the mTOR pathway and benign tumor formation in multiple organs [ 8 ]. WebOssification of the posterior longitudinal ligament (OPLL) OPLL is a condition in which the flexible structure of the posterior longitudinal ligament becomes thicker and less flexible. … literary chronology hebrew bible authorship
Anatomical snuffbox - Wikipedia
WebWhat is tuberous sclerosis complex? Tuberous sclerosis complex (TSC) is a hereditary condition associated with changes in the skin, brain, kidney, and heart. Seizures are a frequent complication, and some people with TSC have learning disabilities. Skin changes are the most noticeable sign of TSC and appear in nearly all people with the condition. Webdiagnosed with TSC These recommendations are for the care of patients who have already been . diagnosed with definite or possible TSC. They include recommendations for surveillance and treatment, and some particular issues for discussion with patients and their families or carers. There is a wide range of different clinical presentations of TSC. WebFeb 13, 2024 · The treatment of tuberous sclerosis complex (TSC) using mammalian target of rapamycin (mTOR) inhibitors is clinically promising. The aim of the present study was to evaluate the efficacy and safety of mTOR inhibitors for improving the clinical symptoms of TSC. We performed a systematic search of major electronic databases (PubMed, … importance of pathophysiology in medicine