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WebThe inhibition of efflux pumps can be achieved by different mechanisms as shown in ( Fig. 2 ): 1 interference with the regulatory steps needed for the expression of the efflux pump, 2 chemical changes in the antibiotic structure hence hindering its attachment as the specific substrate, 3 disruption of the assembly of the efflux pump-components, 4 … Web21 sep. 2024 · Seligmann JF, Fisher D, Brown L, et al. Inhibition of WEE1 is effective in TP53 and RAS mutant metastatic colorectal cancer (mCRC): a randomised phase II trial (FOCUS4-C) comparing adavosertib (AZD1775) with active monitoring. Presented at: 2024 ESMO Congress; September 16-21, 2024; Virtual. Abstract 382O. WebLangdon SP and Smyth JF 1995, ' Inhibition of cell signaling pathways. ', Cancer treatment reviews, vol. 21, pp. 65-89. Inhibition of cell signaling pathways. / Langdon SP and Smyth JF. In: Cancer treatment reviews, Vol. 21, 1995, p. 65-89. Research output: Contribution to journal › Article › peer-review. hsn code for smartwatch