Web16 aug. 2024 · DNA sequences with consecutive guanine bases develop four-stranded G-Quadruplexes (G4) via Hoogsteen base-pairing. They are noncanonical secondary … WebThe TERT gene provides instructions for making one component of an enzyme called telomerase. Telomerase maintains structures called telomeres, which are composed of repeated segments of DNA found at the ends of chromosomes. Telomeres protect chromosomes from abnormally sticking together or breaking down (degrading).
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WebHtert Rpe1 P53, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, ... Structure of the TIN2 TRFH … Web11 feb. 2002 · The 5′-promoter region of the human gene encoding TERT, hTERT, includes binding sites for several transcriptional factors that regulate its expression; in addition, … simplify 25/150
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WebhTERT expression and protein production by CDDO-Me may be attributed to the inhibition of these transcription factors. The role of Sp1 in transcription of hTERT gene has been well-documented. Sp1 interacts with c-Myc to enhance hTERT expression [25,26]. On the other hand, the role of Sp3 and Sp4 in hTERT expression has not been investigated. Web4 apr. 2024 · Organ-on-chip technology can mimic complicated structures and provide researchers with physiologically relevant three-dimensional (3-D) tissue models. The Nortis ParVivo Human Kidney Chip utilizes human telomerase reverse transcriptase (hTERT)–immortalized kidney cells to generate renal proximal tubules (RPTs) for use in … Web10 jan. 2024 · STRUCTURE OF THE HUMAN TELOMERASE THUMB DOMAIN PDB DOI: 10.2210/pdb5UGW/pdb Classification: TRANSFERASE Organism (s): Homo sapiens Expression System: Escherichia coli Mutation (s): No Deposited: 2024-01-10 Released: 2024-02-08 Deposition Author (s): Skordalakes, E., Hoffman, H. raymond remodeling