WebFeb 2, 2011 · On the other hand, one of the targets of CaMKIV is the transcription factor cAMP response element (CRE)-binding protein (CREB). The PGC-1α gene possesses a binding site for CREB, which is well conserved between humans (spanning the region −133 to −116 in PGC-1α promoter) and mice (region −146 to −129) and renders PGC-1α … WebJul 20, 2024 · The transcription coactivators CREB binding protein (CBP) and p300 are highly homologous acetyltransferases that mediate histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and promoters.
Regulatory motifs for CREB-binding protein and Nfe2l2 …
WebDec 1, 2004 · Döring P, Treuter E, Kistner C, Lyck R, Chen A and Nover L 2000 Role of AHA motifs for the activator function of tomato heat stress transcription factors HsfA1 and HsfA2;Plant Cell 12 265–278. Article PubMed PubMed Central Google Scholar Ellis R J 2000 Chaperone substrates inside the cell;Trends Biochem. WebAug 1, 2001 · The structure of CREB complexed with its co-activator the CREB-binding protein has provided new insights into potential mechanisms underlying signal discrimination. And the development of cellular ... genetec cut sheets
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
WebCREB is an upstream regulator across brain regions and is predicted to be upregulated in resilience (R) versus control (C) conditions in the PFC. f, mRNA levels of CREB1 in the … WebThe cAMP response element (CRE)-binding protein (CREB), also known as CREB1, is a 43-kDa basic leucine zipper (bZIP) transcription factor (TF). It is involved in the activation … WebAn overlap of the binding motif of NF-E2 with the half-site CRE2 suggests that competition for binding may exist between Nfe2l2 and CREB. To test this we designed a 19-bp oligonucleotide probe, NFCRE, which covered both NF-E2 and CRE2, for a gel shift and supershift assay (Fig.6A). The band shifts with the NFCRE probe were very similar to the ... genetec crash course