http://www.buffalorodent.com/ WebBuffalo/ Mna rats do not show age-related thymic involution, but rather develop thymic hyperplasia with advancing age. This thymic growth is expansile and there is no infiltration of the surrounding tissues. Because the enlarging thymus occupies the thoracic cavity, most of the rats die of respiratory failure by the age of 24 months.
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Buffalo Rat - an overview ScienceDirect Topics
WebThe Buffalo rat is used in carcinogenesis and oncology research and anticancer drug discovery. Buffalo Rat Charles River Sorry, you need to enable JavaScript to visit this website. WebOct 1, 1980 · Female Buffalo rats, 50-55 days old, were given a single ip injection of NMU (10 mg/100 g). All of the treated rats developed breast cancer. Fifty percent (15 of 30) showed greatly elevated RTW, averaging 5 times the RTW of vehicle-injected controls. Moreover, histological changes analogous to those of human Hashimoto's roiditis were … WebAt the pre-thymoma stage BUF rats have extremely large thymuses due to a gene Ten-1 located on chromosome 1. This gene may be identical to Tsr-1 ( Murakumo et al, 1993, … unh address student financial services